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How Mesotherapy can stimulate collagen production and improve skin elasticity

Updated: Nov 13, 2023




Mesotherapy is a treatment in which the active chemicals are injected into the skin several times in very small doses. Microinjections cause superficial "injuries" to the skin, prompting the body's repair mechanisms. In order to fix the microscopic tissue damage, this response triggers the formation of collagen. Increasing blood flow to the location. Collagen synthesis relies on the delivery of oxygen and nutrients to skin cells, both of which are enhanced by better circulation.


The mixture of compounds injected during Mesotherapy frequently contains growth factors and amino acids that have a role in collagen formation. Collagen proteins are made up of amino acids.

Hyaluronic acid is a naturally occurring chemical in the skin that aids in moisture retention and is frequently used in many Mesotherapy treatments. Maintaining skin elasticity and health requires adequate fluid intake.


Both the microinjuries and the active substances enhance the body's natural ability to heal and rejuvenate. Mesotherapy can enhance the skin's firmness and structural integrity because it increases collagen formation, a protein that is vital to the skin's extracellular matrix.


Fibroblasts are the skin cells that make elastin and collagen. Using mesotherapy, we can stimulate these fibroblasts to produce more collagen. Mesotherapy solutions might vary in composition based on the underlying skin concern and the preferences of the practitioner. In addition, everyone responds differently, and clients will likely require more than one treatment to see optimal results.


Some mesotherapy ingredients stimulate collagen production. Certain amino acids and peptides may stimulate the skin to produce more collagen. Copper peptides could improve collagen formation and wound healing. Alongside hydrating, hyaluronic acid can also increase collagen production. Skin is composed of hyaluronic acid, which plumps and firms it. Growth factors are proteins essential for development of cells, proliferation, and division. Vitamins and minerals are needed for collagen synthesis. Vitamin C is an antioxidant and collagen activator. zinc and copper also play a role in collages synthesis. amino acids act as bonds for proteins including collagen.


Some mesotherapy concoctions contain amino acids that promote collagen synthesis and skin health. Dimethylaminoethanol (DMAE) is thought to firm the skin. It stimulates acetylcholine synthesis, which affects muscle tone and skin flexibility. Retinol, a vitamin A derivative, boosts collagen formation and cell turnover.


Glycerin is a humectant, which means it draws and retains moisture in the skin. It is often used to increase hydration and prevent dryness in skincare products, including mesotherapy solutions. Panthenol (Pro-Vitamin B5) has moisturising qualities. It penetrates the epidermis and is converted to vitamin B5, which aids in the attraction and retention of water. Panthenol is frequently used in skincare formulas to increase hydration and skin soothing. Vitamins with antioxidant qualities, such as vitamin E, can help protect the skin from damage from the environment. Furthermore, they may help to keep the skin hydrated by avoiding water loss. Minerals such as salt and potassium help to maintain the skin's electrolyte balance, which is necessary for adequate hydration.


Vitamin C is a powerful antioxidant that aids in the neutralisation of free radicals produced by sun exposure and pollutants in the environment. It also aids in collagen formation, which contributes to skin firmness and suppleness. Another potent antioxidant that helps protect the skin from free radical damage is vitamin E. It can help improve the skin's moisture retention. Coenzyme Q10 is an antioxidant that occurs naturally in the body. It is involved in the creation of energy within skin cells and helps protect the skin from oxidative damage. Green tea includes polyphenols that have antioxidant and anti-inflammatory properties, such as epigallocatechin gallate (EGCG). Green tea extract can assist in protecting the skin from environmental harm.


Copper peptides are associated to better wound healing and collagen formation. It is thought to boost collagen and elastin formation while also facilitating cellular repair.

Proteins that affect cell development and proliferation are known as growth factors. Growth factors that promote cellular repair and regeneration may be incorporated in mesotherapy treatments. The building blocks of DNA and RNA are nucleotides. Nucleotides are believed help in the repair and regeneration of damaged skin cells when used in mesotherapy formulations. Retinol is well-known for its ability to encourage the production of new, healthy skin cells by increasing cell turnover and It is frequently used in mesotherapy solutions to help with cellular healing.


Written by Angela Blemmings

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